Studies in cardiac pathology . f this processin which the redundant endocardial folds both on the septum andon the ventricular wall form small pockets—actual sacculationswhich are reproductions in miniature of the valves believes that these pockets indicate a functionally compensatingaction on the part of the endocardium, through the agency ofwhich the regurgitation of blood is diminished. He attributestheir genesis to a process similar to that by means of which thesemilunar valves develop in the fetal heart. (Before the truncus arteriosus divides, four folds of gelatinoustissue
Studies in cardiac pathology . f this processin which the redundant endocardial folds both on the septum andon the ventricular wall form small pockets—actual sacculationswhich are reproductions in miniature of the valves believes that these pockets indicate a functionally compensatingaction on the part of the endocardium, through the agency ofwhich the regurgitation of blood is diminished. He attributestheir genesis to a process similar to that by means of which thesemilunar valves develop in the fetal heart. (Before the truncus arteriosus divides, four folds of gelatinoustissue covered by endocardium are formed, two of which, on di-vision of the truncus arteriosus into the aorta and the pulmonaryartery, are cut in half, so that each vessel gets three folds whichsubsequently take on the form of pockets, a metamorphosis inwhich the mechanical action of the blood-stream jDrobably playsa role.) 1 Zahn: Verhandlung. d. Kongr. f. inn. Med., , p. Schminke: Virchows Archives, 1908, cxcii, p. Fig. 17.—Sclerotic Endocarditis. L. B., male, Italian, aged seventy-seven years. (Philadelphia Hospital vol. xxiv, p. : Dr. A. A. Eshner. Pathologist: Dr. H. T. Karsner.) Clinical Notes: Patient was admitted in a delirious condition. The heart is enlargedand its sounds are weak. No distinct murmurs are heard. The urine is albuminous. Hem-oglobin, 68 per cent.; erythrocytes, 5,200,000. Death occurred gradually, preceded bj anextensive and a generalized purpuric cutaneous erruption. Pathologic Diagnosis: Emphysema, hypostatic pneumonia, chronic interstitial myo-carditis, sclerotic endocarditis of all the valves, chronic interstitial nephritis, etc. Heart: Weighs 360 gm. The left ventricle 13 mm. The mitral orifice 11 leaflets and chordae tendineae show slight general thickening and rd r:icl ion. The i)aiiillarymuscles are fibrosed. The aortic orifice measures cm. Its IcoJIcIk mr ,! <tiiil nl Iheirbases sligh
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