. Infection, immunity and serum therapy : in relation to the infectious diseases of man . tical haptophores. Immunization with leuco-cyte?, cells which contain complement, also causesthe formation of anticomplement. Both naturaland acquired antibacterial immunity may be low-ered by the injection of anticomplement which ishomologous to the complement of the animal. Some time ago, Ehrlich expressed the opinionthat an amboceptor in certain cases may have morethan one cornplementophilous haptophore; inother words, that it may be a polyceptor ratherthan an amboceptor. This has again been empha-size
. Infection, immunity and serum therapy : in relation to the infectious diseases of man . tical haptophores. Immunization with leuco-cyte?, cells which contain complement, also causesthe formation of anticomplement. Both naturaland acquired antibacterial immunity may be low-ered by the injection of anticomplement which ishomologous to the complement of the animal. Some time ago, Ehrlich expressed the opinionthat an amboceptor in certain cases may have morethan one cornplementophilous haptophore; inother words, that it may be a polyceptor ratherthan an amboceptor. This has again been empha-sized recently by way of explaining the ability ofan amboceptor to absorb from a normal serum notonly the complement which serves to activate theamboceptor, but also others which happen to bepresent in the serum. The former is spoken of asthe dominant complement and the latter as non- 270 1A FE( TION AND UX1TY. dominant complements. Figure 8 is an illustra-tion of such a If one immunizes with an immune serum theproduct is spoken of in a general way as an anti-. Fig. 8.—Illustrating the amboceptor with more than onecomplementophilous haptophore (a polyceptor). a, Cell re-ceptor ; 6, cytophiHus haptophore of the amboceptor; c, thedominant complement; d, the non-dominant complements;, the heptophore of the amboceptor for the dominant com-plement;/?, those for the non-dominant complements. (FromEhrlich and Marshall.) immune serum. The latter contains, as stated,anticomplement, and through the agency of thissubstance the antiserum antagonizes the action ofthe serum which was used for the immunization. AX TI AMBOCEPTORS. 271 Inasmuch, however, as the immune serum containsamboceptors also, the antagonistic action of theantiserum may depend, in part, on the presence ofantiamboceptors. Differentiation between the ac-tion of anticomplement and antiamboceptor is dif-ficult, but it may be accomplished in certain casesby appropriate binding experiments. Serum 1, a
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