. The elements of materia medica and therapeutics (Volume 2) . as a medicine. Its physiological effects, according to Dr. Roth,(Dis. Inaug. de Indico, 1834, Berol.; and Brit, and For. Med. Rev. vol. ii. p. 244,) are as fol-lows :—Shortly after taking it the patient experiences a sense of constriction at the fauces, andthe impression of a metallic taste on the tongue. These are followed by nausea, and frequentlyby actual vomiting. The intensity of these symptoms varies in different cases. In some thevomiting is so violent as to preclude the further use of the remedy. The matter vomited pre-sent


. The elements of materia medica and therapeutics (Volume 2) . as a medicine. Its physiological effects, according to Dr. Roth,(Dis. Inaug. de Indico, 1834, Berol.; and Brit, and For. Med. Rev. vol. ii. p. 244,) are as fol-lows :—Shortly after taking it the patient experiences a sense of constriction at the fauces, andthe impression of a metallic taste on the tongue. These are followed by nausea, and frequentlyby actual vomiting. The intensity of these symptoms varies in different cases. In some thevomiting is so violent as to preclude the further use of the remedy. The matter vomited pre-sents no peculiarity except in its blue colour. When the vomiting has subsided, diarrhoeausually occurs; the stools are more frequent, liquid, and of a blue or blackish colour. Thevomiting and diarrhoea are frequently accompanied by cardialgia and colic. Occasionally thesesymptoms increase, and the use of the remedy is in consequence obliged to be omitted. Dys-pepsia and giddiness sometimes succeed. The urine has a brown, dark, violet colour; but Dr. Fig. Indigofera tinctoria. THE TURPENTINE PISTACIA. 611 Roth never found the respiratory matter tinged with it. After the use of indigo for a fewweeks, twitchings of the muscles sometimes were observed, as after the use of strychnia. Ithas been employed principally in spasmodic affections—viz. epilepsy, convulsions of children,chorea, and hysteria. In epilepsy it has been tried by Von Stahly, Lenhossek, Grossheim,Ideler, Wolf, Leinewcber, Doepp, (Roth, op. cit.; Dierbach, Neuest. Enid, in d. Mat. Bd. 1, , 1837), and Noble {Lond. Med. Gaz. vol. xvii. p. 1038), with good effect. Some of the suc-cessful cases were of very long standing. Roth says, that at the commencement of the treat-merit, the frequency of the paroxysms was invariably increased. Idiopathic epilepsy is said tohave been more benefited by it than the symptomatic epilepsy. I have ^ried it in a considerablenumber of epileptic cases at the London Hospital, but


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