. Pathological technique; a practical manual for workers in pathological histology and bacteriology. \ coccus pyogenes in morphology, but differing definitely fromthem in cultural and other peculiarities. It has been foundchiefly in lobar pneumonia, but occurs in other inflammatoryprocesses and probably has been sometimes mistaken forthe pneumococcus or the streptococcus pyogenes. Oscar Richardson points out the following chief character-istics by which it may be distinguished from the pneumo-coccus and the streptococcus pyogenes: 1. The capsules persist in cultures (see Fig. 46). 2. On the su


. Pathological technique; a practical manual for workers in pathological histology and bacteriology. \ coccus pyogenes in morphology, but differing definitely fromthem in cultural and other peculiarities. It has been foundchiefly in lobar pneumonia, but occurs in other inflammatoryprocesses and probably has been sometimes mistaken forthe pneumococcus or the streptococcus pyogenes. Oscar Richardson points out the following chief character-istics by which it may be distinguished from the pneumo-coccus and the streptococcus pyogenes: 1. The capsules persist in cultures (see Fig. 46). 2. On the surface of coagulated blood-serum its coloniesare flat, colorless, viscid, mucus-like, of irregular outline,. Fig. 46.—Streptococcus capsulatus, from a blood culture in a case of pneu-monia; stained by W. H. Smiths method; X about 700 (W. H. Smith; photoby L. S. Brown). and may attain a diameter of 2 or 3 mm. They may becomeconfluent and form large patches of mucus-like material(see Fig. 44). 3. In glucose-agar stab, adjusted to a reaction of acidto phenolphthalein,. there is growth all along the line ofinoculation, from which, in places, fusiform or hemisphericalmasses of growth extend into the surrounding medium in avertical plane, apparently occupying clefts in the medium(Fig. 45). It is very important for the development ofthese characteristic appearances that the glucose-agar be 272 PA THOLOGICAL TECHNIQUE. known to have at the time of inoculation a reaction veryclose to that above indicated. Gonococcus.—Morphology.—Cocci of medium size, com-posed usually of two hemispheres separated by a narrowunstained interval. Sometimes two of these pairs of hemi-spheres are joined together


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