. A text-book of practical therapeutics, with especial reference to the application of remedial measures to disease and their employment upon a rational basis . the cord, and B, the muscular 1 •, ,- * ,i • i 1 i • 1 fibres in the uterus itself. lumbar portion of the spinal cord which con-trols this viscus. On the uterus ergot in full medicinal dose exerts its influence not byincreasing the normal pains of labor, but by causing a tetanic, tonic,unyielding uterine spasm which drives all before it. In very smalldoses it may assist the normal contractions without causing them tobecome tetanic. Erg
. A text-book of practical therapeutics, with especial reference to the application of remedial measures to disease and their employment upon a rational basis . the cord, and B, the muscular 1 •, ,- * ,i • i 1 i • 1 fibres in the uterus itself. lumbar portion of the spinal cord which con-trols this viscus. On the uterus ergot in full medicinal dose exerts its influence not byincreasing the normal pains of labor, but by causing a tetanic, tonic,unyielding uterine spasm which drives all before it. In very smalldoses it may assist the normal contractions without causing them tobecome tetanic. Ergot acts as a stimulant to all unstriped muscular fibres. Acute Poisoning.—The symptoms of overdosing from ergot, whenthe effects are slowly produced, are sometimes great hunger or cravingof food, at other times nausea and vomiting, If the poisoning is quitesevere, there are great restlessness, headache, delirium, and coldnessof the surface of the body. Chronic Poisoning.—Two forms of poisoning from the prolongeduse of ergotized rye bread sometimes occur. One is characterized byspasmodic muscular contractions, the other consists in the formation. ERGOT. 235 of gangrenous sloughs. In the first of these forms it is not very uncom-mon for cataract to develop, and it is stated that the spams are due tothe influence of one of the principles of ergot—namely, cornutine. Therapeutics.—Ergot is given to parturient women for the preventionor arrest of post-partum hemorrhages. For the prevention it should begiven to the woman by the mouth just as the head of the child is about toslip over the perineum, and not before, but in the majority of instancesits use is needless. When administered to check a hemorrhage alreadyflowing, the doses should be large, as much as 1 to 2 drachms ()of the fluid extract or 1 wineglassful () of the wine of ergot. Thedrug should produce its effects in about fifteen minutes, and may berepeated every fifteen minutes till it acts. The actio
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