Gynecology . ype of sarcoma springs from themucosa of the cervix the vagina be-comes filled with a mass of grape-likepolyps, which eventually protrudethrough the introitus into the outerworld. The tumor under these condi-tions is commonly called a grape-moleor sarcoma botryoides. Diffuse sarcoma of the endometriumspreads into the wall of the uterusperipherally in the same manner as aninverting adenocarcinoma of the body. Myosarcoma.—Sarcomatous degeneration of fibroid tumors—myosarcoma—usually starts near the center of the growth. It may appear as a sharply definednodule or it may spread diffu
Gynecology . ype of sarcoma springs from themucosa of the cervix the vagina be-comes filled with a mass of grape-likepolyps, which eventually protrudethrough the introitus into the outerworld. The tumor under these condi-tions is commonly called a grape-moleor sarcoma botryoides. Diffuse sarcoma of the endometriumspreads into the wall of the uterusperipherally in the same manner as aninverting adenocarcinoma of the body. Myosarcoma.—Sarcomatous degeneration of fibroid tumors—myosarcoma—usually starts near the center of the growth. It may appear as a sharply definednodule or it may spread diffusely in the surrounding tissue. Various forms ofdegeneration are apt to take place, so that, macroscopically, the sarcomatousportion of the tumor is sometimes distinguished from the normal tissue by dis-colored appearances, necrosis, or accumulation of fluid. Histology.—The cells of which the uterine sarcomata are made up are con-siderably varied. Meyer divides the growths into muscle-cell sarcoma (in. Grape Sarcoma, or Sarcoma vagina is seen crowded with grape-like masses of the growth. (Copied from adrawing in Kustners Handbuch.) Fig. 280 GYNECOLOGY which muscle cells and sarcoma cells are mixed), spindle-cell sarcoma, and round-cell sarcoma. The cells may be of all kinds and sizes. Sarcomata of the endo-metrium are chiefly characterized by round cells. The latter type of sarcoma (especially the diffuse kind) is sometimes differen-tiated with difficulty from adenocarcinoma of the body, which in the advancedstages loses its glandular characteristics, the appearance and arrangement ofthe cells appearing quite similar to round-cell sarcoma. On the other hand,the cells of diffuse sarcoma of the endometrium may assume an alveolar
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