Gall-stones and diseases of the bile-ducts . g. Hillier andGroodall have conducted a valuable investigationconcerning the histology and general features ofcarcinoma of the pancreas, and they have come tothe conclusion that primary cancer of this gland mayarise in each of the three epithelial structures whichit contains. The common type is spheroidal-celledcarcinoma with a large amount of fibrous tissue;this probably arises in the acini of the gland and iscomparable to spheroidal-celled cancer of the second variety is columnar-celled and probablyarises from the duct; in structure thi
Gall-stones and diseases of the bile-ducts . g. Hillier andGroodall have conducted a valuable investigationconcerning the histology and general features ofcarcinoma of the pancreas, and they have come tothe conclusion that primary cancer of this gland mayarise in each of the three epithelial structures whichit contains. The common type is spheroidal-celledcarcinoma with a large amount of fibrous tissue;this probably arises in the acini of the gland and iscomparable to spheroidal-celled cancer of the second variety is columnar-celled and probablyarises from the duct; in structure this kind re-sembles primary cancer of the duodenum. 140 DISEASES OF THE BILE-DUCTS The third variety is of interest as there is goodreason to believe that is arises in Langerhansislands; it consists of cells most irregular in sizeand shape, but on the whole much larger than in theother varieties of carcinoma, and possessed of nucleiwhich in some instances are enormous/ Islet Connectivetissue Duct 0h-> ./ o\ „ ,-„--- cell. .— Duct Zone of al-veolar cells Fig. 43.—A magnified view of a cross-section of the pancreas, show-ing its various epithelial elements (after Bohn and Davidoff). In connection with the relation of the islands tocarcinoma, it is iDointed out that in the ordinaryvarieties of cancer of the pancreas the islands remainunaffected, and may be seen in some instancessurrounded by cancerous growth; on the otherhand, when the pancreas is the seat of secondarycancer the islands are among the first of the pan-creatic structures to disappear. CANCER OF THE PANCREAS 141 Cancer of the pancreas attacks the head of thegland six times more frequently than the tail. Inone unusual case a cancerous deposit was found inthe head and tail of the same gland (Hale White).Hillier and Coodall observe that the site of originfor the head corresponds closely with the position ofthe junction of the ducts of Wirsung and Santorini. Clinical features. —The difficulty of
Size: 1956px × 1277px
Photo credit: © The Reading Room / Alamy / Afripics
License: Licensed
Model Released: No
Keywords: ., bookcentury1900, bookdecade1900, bookpublishernewyorkwilliamwood
