. University of Toronto studies. Physiological series. no. 1-98. 1900-28 . Dog 39 A Slight dilatation Slight dilatation A Dilatation Dilatation A Dilatation and con-striction Very marked dilatation B Dilatation and con-striction Dilatation and constric-tion * Unless otherwise stated dilatation means active = 1: 100,000 = 1: 10,000 adrenalin. ADRENALIN VASODILATOR MECHANISMS 509 peripheral mechanism has a much more limited action than the gangUar-peripheral mechanisms when taken together. After denervation of greater duration. Animals (six dogs and t
. University of Toronto studies. Physiological series. no. 1-98. 1900-28 . Dog 39 A Slight dilatation Slight dilatation A Dilatation Dilatation A Dilatation and con-striction Very marked dilatation B Dilatation and con-striction Dilatation and constric-tion * Unless otherwise stated dilatation means active = 1: 100,000 = 1: 10,000 adrenalin. ADRENALIN VASODILATOR MECHANISMS 509 peripheral mechanism has a much more limited action than the gangUar-peripheral mechanisms when taken together. After denervation of greater duration. Animals (six dogs and threecats) were studied which had had the sciatic and femoral nerves severed I iMHl^^^^l^^^^^^^^HHi ^ \^ ? ^.^0^i^ pgkm^^^^^^ ^tyi.:kii$^0f< («?WW^.-!J ^^Sw.;**^^ WovvttnV W\\) ._- — -^ -___ uev\\e«^ Vivvyvn . —-^ ? ??^mm^^ --—^ 5 sec. J_J—1_J 1 1 1_1 1_ 1 1 1 1 1_J 1 1_L _I— 1. 1 II BHl 1 1 1 Fig. 4. Dilatation of the hind limb of a cat ( kgm.) to cc, adrenalin,1: 100,000, seven days after denervation. (Reduced one-half). Fig. 5. Dilatation of the hind limb of a dog (14 kgm.) to cc. adrenalin,1: 50,000, twenty-two days after denervation. (Reduced one-half) in one limb from seven to thirty days before. It can be seen from thefollowing table (table 1) that although the lapse of a week in mostcases renders the peripheral dilator mechanism more effective (seefigs. 4 and 5), a greater amount of time does not materially increase the 5|0 r. A. IIARTMAN, L. G. KILBORN AND LOIS FRASER
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