Hooper's physician's vade mecum, or, A manual of the principles and practice of physic . isease. But the agency of deposits of fat in pro-ducmg organic disease is not limited to the secret-ing organs. It extends also to the several tissuesof the body. Those deposits are laid down, forinstance, in the structure of the heart, constitutingfatty degeneration of that organ, and enfeebling itby encroaching on the space which in health isoccupied by muscular fibres. The degeneratedmuscular structure is a frequent seat of calcareousdeposit. The form which this fatty degenerationof the muscular textuie
Hooper's physician's vade mecum, or, A manual of the principles and practice of physic . isease. But the agency of deposits of fat in pro-ducmg organic disease is not limited to the secret-ing organs. It extends also to the several tissuesof the body. Those deposits are laid down, forinstance, in the structure of the heart, constitutingfatty degeneration of that organ, and enfeebling itby encroaching on the space which in health isoccupied by muscular fibres. The degeneratedmuscular structure is a frequent seat of calcareousdeposit. The form which this fatty degenerationof the muscular textuie of the heart assumesunder the microscope, is shown in the subjoinedengravings from a paper in the Medical Gazette, 1849, by Dr. Ormerod. 346. Fatty deposits are also of frequent occurrence in the coats ofarteries, which are often found subject to this species of degeneration insubjects affected by similar disease of the liver and kidney. 347. The situation of these deposits in the arteries is either the cel-lular membrane between the inner and middle coats, or the fibres of the. 80 PHYSIOLOGY AND GENERAL PATHOLOGY. middle coat itself. They are known as atheromatous they occur in the middle coat of the larger arteries, they takethe place of the healthy structure, impair its elasticity, and lead todilatation of the vessel. In the smaller vessels they are often earnedto such an extent as to obliterate their cavities, and thns to cut off thesupply of blood from the parts to which they are distributed. Thus,when the coronary artery of the heart is the seat of atheromatousformations, the muscular substance of the heart itself becomes atro*phied. This class of deposits is found to obey the law of symmetry,attacking equally and similaily the vessels of both sides of the body. 348. The atheromatous deposits in the coats of the arteries oftenbecome the seats of ulceration, leading to perforation of the vessels andsudden death from haemorrhage. When the ulcers mak
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