Diseases of the nervous system : a text-book of neurology and psychiatry . Fig. 48.—Exophthalmic goitre, show-ing marked exophthalmos and enlargedthyroid. (Courtesy of Dr. George ) Fig. 49.—Same patient four monthsafter operation (extirpation). Greatlydiminished exophthalmos and change offacial expression. (Courtesy of W. Crile.) The eye symptoms consist of a marked and variable protrusion ofthe eyeball, with widened orbital fissure, sometimes greater on oneside than the other, and felt as a disagreeable pressure and tension bythe patient. The eyelids are at times swollen, an


Diseases of the nervous system : a text-book of neurology and psychiatry . Fig. 48.—Exophthalmic goitre, show-ing marked exophthalmos and enlargedthyroid. (Courtesy of Dr. George ) Fig. 49.—Same patient four monthsafter operation (extirpation). Greatlydiminished exophthalmos and change offacial expression. (Courtesy of W. Crile.) The eye symptoms consist of a marked and variable protrusion ofthe eyeball, with widened orbital fissure, sometimes greater on oneside than the other, and felt as a disagreeable pressure and tension bythe patient. The eyelids are at times swollen, and the upper, andpossibly the lower lids largely retracted (Dalrymple, Stellwag)independently of and often preceding the protrusion of the upper lid also does not move synchronously with the lowering orthe raising of the eyeball (von Graefes symptom), following moreslowly or receding more rapidly (spasticity) than the moving eyeball,in the presence or absence of protrusion. Both signs may be unequallypresent. The relative infrequency of winking (Stellwag


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